PT  - JOURNAL ARTICLE
AU  - Aktas, Aynur
AU  - Beeler, Dori
AU  - Waldman, Jake
AU  - Walsh, Declan
TI  - Vagus nerve and cancer symptom science
AID  - 10.1136/spcare-2025-005483
DP  - 2025 May 02
TA  - BMJ Supportive & Palliative Care
PG  - spcare-2025-005483
4099  - http://spcare.bmj.com/content/early/2025/05/01/spcare-2025-005483.short
4100  - http://spcare.bmj.com/content/early/2025/05/01/spcare-2025-005483.full
AB  - Patients with cancer are often polysymptomatic due to significant disease and treatment-related morbidity. Vagus nerve stimulation (VNS), a type of neuromodulation, affects various physiological processes that are highly relevant to many cancer-related symptoms. It is an emerging therapy that uses the omnipotent nature of the nerve and is known to ameliorate conditions such as depression, epilepsy, gastrointestinal disorders and migraine. Given the evidence base for VNS and its proven utilisation outside of cancer, we suggest research and clinical application of this treatment modality in supportive oncology.Data are available in a public, open access repository.